Topiramate (the TPM) is a naturally existing monosaccharide D-fructose sulfide, and together with felbamate, lamotrigine and vigabatrin are current several broad-spectrum anti-epileptic drugs with relatively wide clinical application and can be used to control different types of epilepsy with excellent efficacy and pharmacokinetics.
This product is generally used for the adjuvant treatment of antiepileptic drugs and is effective in treating simple and complex seizures as well as systemic tonic-clonic seizures and can also be used for the treatment of infantile spasms. Features of this product include excellent long-term efficacy, no significant resistance as well as being able to be used alone for antiepileptic purpose.
But in cases of being applied to children or fast increase of the amount can cause cognitive impairment and neurotoxicity, and easy to trigger kidney stones.
Topiramate Applications:
In 1980, scientists had first successfully synthesized topiramate in the laboratory. It had been applied to patients with epilepsy for the first time in 1986. In 1995, it was approved for entering into the market of UK for the first time. Its basic structure is fructopyranose sulfamate. Unlike other kinds of anti-epileptic drug, TPM has various kinds of anti-epileptic mechanisms including blocking the voltage-dependent sodium channels, enhancing the activity of GABA in the location of the γ- aminobutyric acid A (GABAA) receptor as well as blocking the activity of the AMPA glutamate receptor. In addition, there is still mild effect of carbonic anhydrase inhibitors.
Europe and the United States had conducted double-blind, placebo-controlled studies and demonstrated that the adjunctive therapy with topiramate has excellent efficacy, safety and is well tolerated in the treatment of various types of refractory epilepsy. Now it has begun with topiramate monotherapy and has also achieved good results with 62% of patients with epileptic seizures disappearing completely.
Our order process:
Step 1
Please tell me in what products you are interested including CAS number, quantities, and the destination country.
Step 2
You confirm all details and offer us purchase order.
Step 3
We offer the quotation of products and suitable shipping method for reference.
Step 4
You confirm the order and pay money 100% in advance and send us your contact information including contacting person,address,mobile number etc.
Step 5
We arrange the shipment according to your requirements and tracking number will be offered after confirming the payment within 24h
Step 6
We offer after-sales service after you receive products.
Our competitive advantages:
Rich experience
Our company is a professional raw powder factory in China for over 10 years, all powders are factory directly supplying.
Wide range of export
Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.
High customs pass guaranteed.
Professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed. 100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil; 98% pass to Germany, Russia, Australia, New Zealand.
Fast leading time
Most of powders are in stock, Chargeable samples are available, Could be shipped out within 24hours.
High quality, good price, fast and safety delivery.
Shipment by EMS ,FEDEX,DHL,TNT, UPS ,etc
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High Quality Topiramate CAS 97240-79-4 for Weight Loss and Antiepileptic
Topiramate (the TPM) is a naturally existing monosaccharide D-fructose sulfide, and together with felbamate, lamotrigine and vigabatrin are current several broad-spectrum anti-epileptic drugs with relatively wide clinical application and can be used to control different types of epilepsy with excellent efficacy and pharmacokinetics.
This product is generally used for the adjuvant treatment of antiepileptic drugs and is effective in treating simple and complex seizures as well as systemic tonic-clonic seizures and can also be used for the treatment of infantile spasms. Features of this product include excellent long-term efficacy, no significant resistance as well as being able to be used alone for antiepileptic purpose.
But in cases of being applied to children or fast increase of the amount can cause cognitive impairment and neurotoxicity, and easy to trigger kidney stones.
Topiramate Applications:
In 1980, scientists had first successfully synthesized topiramate in the laboratory. It had been applied to patients with epilepsy for the first time in 1986. In 1995, it was approved for entering into the market of UK for the first time. Its basic structure is fructopyranose sulfamate. Unlike other kinds of anti-epileptic drug, TPM has various kinds of anti-epileptic mechanisms including blocking the voltage-dependent sodium channels, enhancing the activity of GABA in the location of the γ- aminobutyric acid A (GABAA) receptor as well as blocking the activity of the AMPA glutamate receptor. In addition, there is still mild effect of carbonic anhydrase inhibitors.
Europe and the United States had conducted double-blind, placebo-controlled studies and demonstrated that the adjunctive therapy with topiramate has excellent efficacy, safety and is well tolerated in the treatment of various types of refractory epilepsy. Now it has begun with topiramate monotherapy and has also achieved good results with 62% of patients with epileptic seizures disappearing completely.
Our order process:
Step 1
Please tell me in what products you are interested including CAS number, quantities, and the destination country.
Step 2
You confirm all details and offer us purchase order.
Step 3
We offer the quotation of products and suitable shipping method for reference.
Step 4
You confirm the order and pay money 100% in advance and send us your contact information including contacting person,address,mobile number etc.
Step 5
We arrange the shipment according to your requirements and tracking number will be offered after confirming the payment within 24h
Step 6
We offer after-sales service after you receive products.
Our competitive advantages:
Rich experience
Our company is a professional raw powder factory in China for over 10 years, all powders are factory directly supplying.
Wide range of export
Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.
High customs pass guaranteed.
Professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed. 100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil; 98% pass to Germany, Russia, Australia, New Zealand.
Fast leading time
Most of powders are in stock, Chargeable samples are available, Could be shipped out within 24hours.
High quality, good price, fast and safety delivery.
