Introduction

 

 

Description:

 Tofacitinib (formerly tasocitinib, CP-690550) is a drug being investigated by Pfizer for the treatment of rheumatoid arthritis (RA), psoriasis, inflammatory bowel disease, and other immunological diseases, as well as for the prevention of organ transplant rejection. It is an inhibitor of the enzyme Janus kinase 3 (JAK3), which means that it interferes with the JAK-STAT signaling pathway that transmits information outside the cell into the cell nucleus, influencing DNA transcription. Recently it has been shown in a murine model of established arthritis, tofacitinib rapidly improved disease by inhibiting the production of inflammatory mediators and suppressing STAT1-dependent genes in joint tissue. This efficacy in this disease model correlated with the inhibition of both JAK1 and 3 signaling pathways, suggesting that tofacitinib may exert therapeutic benefit via pathways that are not exclusive to inhibition of JAK3.

Application

 

Storage method: 

Below 30 ºC storage.

Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us. 
 
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , 
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
 
Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.

Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price. 

Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we'd like to accept bank transfer, Western Union or Paypal or  Moneygram

Q6:How long does it take to the goods arrived ?
A:It is Depending on your location,
    For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q7  Do  you  have  any  reshipment  policy ?  
we have good after-sale service and re-shipment policy if the parcel  lose
Our long association with  our clients has brought great benefits
We always take the upmost care in the packaging of our products 
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible  will seize a small number of packages.
In this circumstance we promise reship free  to establish  long term relationship
 
Q8 :Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost shouldundertake by your side.

As a leading manufacturer of steroid raw materials  .and  Peptides 
We specialized in manufacturing high quality and reliable raw material 
which are widely used in the fields of food, health, cosmetics, pharmaceuticals, and Bodybuilding
 
we have formed a technology and management team that cooperate closely with some  overseas Labs  all speak highly of our safe shipping and goods .
please donot hesitate to contact us.
                                                                                               
                             
                            We have our warehouse in US

                                   Feedback from our dear clients

PACKING

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 5kg/carton(1kg net weight, 1.1kg gross weight, packed in five aluminum foil bag)

3) 25kg/drum (25kg net weight, 28kg gross weight; packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 

DELIVERY

1) ≤50kgs Send by DHL, EMS, FEDEX, TNT.

2) ≥50kgs Ship by air.

3) ≥200kgs Ship by sea.

DELIVERY

 

Send by courier service like FedEx, EMS, UPS, DHL or TNT.


Our Company

Wuhan W&Z Biotech Co,.Ltd is a high-tech enterprise which focus on the R&D, production, sales and service of biomedical and large health field. It has strong scientific research strength, modern management system and high-quality marketing team.

W&Z, located in Wuhan, the national key science and education base, cooperates with Wuhan University, Huazhong University of Science and Technology and other well-known universities, forming a good R&D and production team. in our R & D team, there are five experts in fields.

W&Z focus on provide CRO and CMO services for customers on one-stop intermediates, APIs and green technology. We have established modern R&d laboratories in Wuhan Optical Valley, have two partner factories in Shandong and Sichuan. Besides supplying standard products with mature technology, we also do customize under customer`s personalized needs.

We will uphold the quality first, service-oriented, integrity-based purpose, committed to provide more and more, better and better services to the global customers.





Thanks for your time in advance!

nora 
Mobile Phone +86 18908650780
 
 

Introduction

 

 

Description:

 Tofacitinib (formerly tasocitinib, CP-690550) is a drug being investigated by Pfizer for the treatment of rheumatoid arthritis (RA), psoriasis, inflammatory bowel disease, and other immunological diseases, as well as for the prevention of organ transplant rejection. It is an inhibitor of the enzyme Janus kinase 3 (JAK3), which means that it interferes with the JAK-STAT signaling pathway that transmits information outside the cell into the cell nucleus, influencing DNA transcription. Recently it has been shown in a murine model of established arthritis, tofacitinib rapidly improved disease by inhibiting the production of inflammatory mediators and suppressing STAT1-dependent genes in joint tissue. This efficacy in this disease model correlated with the inhibition of both JAK1 and 3 signaling pathways, suggesting that tofacitinib may exert therapeutic benefit via pathways that are not exclusive to inhibition of JAK3.

Application

 

Storage method: 

Below 30 ºC storage.

Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us. 
 
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , 
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
 
Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.

Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price. 

Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
we'd like to accept bank transfer, Western Union or Paypal or  Moneygram

Q6:How long does it take to the goods arrived ?
A:It is Depending on your location,
    For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q7  Do  you  have  any  reshipment  policy ?  
we have good after-sale service and re-shipment policy if the parcel  lose
Our long association with  our clients has brought great benefits
We always take the upmost care in the packaging of our products 
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible  will seize a small number of packages.
In this circumstance we promise reship free  to establish  long term relationship
 
Q8 :Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost shouldundertake by your side.

As a leading manufacturer of steroid raw materials  .and  Peptides 
We specialized in manufacturing high quality and reliable raw material 
which are widely used in the fields of food, health, cosmetics, pharmaceuticals, and Bodybuilding
 
we have formed a technology and management team that cooperate closely with some  overseas Labs  all speak highly of our safe shipping and goods .
please donot hesitate to contact us.
                                                                                               
                             
                            We have our warehouse in US

                                   Feedback from our dear clients

PACKING

1) 1kg/bag (1kg net weight, 1.1kg gross weight, packed in an aluminum foil bag)

2) 5kg/carton(1kg net weight, 1.1kg gross weight, packed in five aluminum foil bag)

3) 25kg/drum (25kg net weight, 28kg gross weight; packed in a cardboard-drum with two plastic-bags inside; Drum Size: 510mm high, 360mm diameter)

 

DELIVERY

1) ≤50kgs Send by DHL, EMS, FEDEX, TNT.

2) ≥50kgs Ship by air.

3) ≥200kgs Ship by sea.

DELIVERY

 

Send by courier service like FedEx, EMS, UPS, DHL or TNT.


Our Company

Wuhan W&Z Biotech Co,.Ltd is a high-tech enterprise which focus on the R&D, production, sales and service of biomedical and large health field. It has strong scientific research strength, modern management system and high-quality marketing team.

W&Z, located in Wuhan, the national key science and education base, cooperates with Wuhan University, Huazhong University of Science and Technology and other well-known universities, forming a good R&D and production team. in our R & D team, there are five experts in fields.

W&Z focus on provide CRO and CMO services for customers on one-stop intermediates, APIs and green technology. We have established modern R&d laboratories in Wuhan Optical Valley, have two partner factories in Shandong and Sichuan. Besides supplying standard products with mature technology, we also do customize under customer`s personalized needs.

We will uphold the quality first, service-oriented, integrity-based purpose, committed to provide more and more, better and better services to the global customers.





Thanks for your time in advance!

nora 
Mobile Phone +86 18908650780