Raw Peptides Bremelanotide/PT141/PT-141 for female sexual dysfunction

 Cas No. 32780-32-8

  Molecular FormulaC50H68N14O10

  Molecular Weight1025.2

  Purity (HPLC)99.0%min.

  Appearance:Frozen White powder

  Single Impurity (HPLC) 1.0%max



Description:

PT-141 (Bremelanotide) is the first of a new class of drugs called melanocortin agonists being developed to treat sexual dysfunction.The mechanism of action of PT-141 (Bremelanotide) may offer significant safety and efficacy benefits over currently available products because it acts on the pathway that controls sexual function without acting directly on the vascular system.Clinical data indicates that PT-141 (Bremelanotide) may be effective in treating a broad range of patients suffering from ED.

The nasal formulation of PT-141 (Bremelanotide) being developed is as convenient as oral treatments, is more patient-friendly than invasive treatments for ED, such as injections and trans-urethral pellets, and appears to result in a rapid onset of action.Bremelanotide (PT-141) was developed from Melanotan 2 (MT-II).PT-141 is a metabolite of MT-II that lacks the C-terminal amide function-stripping away tanning properties.

PT-141 or Bremelanotide is the generic term for a research peptide being studied for its possible use in helping to improve sexual dysfunction in both men and women. PT-141 was developed from the tanning peptide Melanotan 2, which is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis that is known as alpha-Melanocyte stimulating hormone. MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido.
 


PT-141 Application

PT-141 is a synthetic amino acid protein discovered during clinical trials using the Melanotan 2 for sunless tanning, photo-protection results from melanotans. The melanocortin system targets receptors associated with desire through the melanocyte stimulating hormone paths that cross the blood-brain-barrier. Potentially the powerful sex-drug results feeling an aphrodisiac experience amplifying arousal pt141 reviews have shown the ability to increase libido effects of both men and women
 
Potential benefits

For  Men:

effective in a broad range of patients, including those with severe ED and those non-responsive to sildenafil
efficacy in "at-home" studies is comparable to PDE-5 inhibitors
up to 50% of ED patients were restored to a normal level of function
co-administration with sildenafil shows superior efficacy
side effects include facial flushing, nausea, aftertaste and post-nasal drip

For  Women:

Palatin conducted a Phase 2A study in 18 premenopausal women with a diagnosis of female sexual
dysfunction (FSD). Patients reported a significant increase in sexual desire and in genital arousal after
receiving PT-141, compared to
placebo. Additionally, there was a correlation between sexual desire and genital arousal in patients receiving
PT-141, an observation that further reinforces the potential importance of these reports.

Raw Peptides Bremelanotide/PT141/PT-141 for female sexual dysfunction

 Cas No. 32780-32-8

  Molecular FormulaC50H68N14O10

  Molecular Weight1025.2

  Purity (HPLC)99.0%min.

  Appearance:Frozen White powder

  Single Impurity (HPLC) 1.0%max



Description:

PT-141 (Bremelanotide) is the first of a new class of drugs called melanocortin agonists being developed to treat sexual dysfunction.The mechanism of action of PT-141 (Bremelanotide) may offer significant safety and efficacy benefits over currently available products because it acts on the pathway that controls sexual function without acting directly on the vascular system.Clinical data indicates that PT-141 (Bremelanotide) may be effective in treating a broad range of patients suffering from ED.

The nasal formulation of PT-141 (Bremelanotide) being developed is as convenient as oral treatments, is more patient-friendly than invasive treatments for ED, such as injections and trans-urethral pellets, and appears to result in a rapid onset of action.Bremelanotide (PT-141) was developed from Melanotan 2 (MT-II).PT-141 is a metabolite of MT-II that lacks the C-terminal amide function-stripping away tanning properties.

PT-141 or Bremelanotide is the generic term for a research peptide being studied for its possible use in helping to improve sexual dysfunction in both men and women. PT-141 was developed from the tanning peptide Melanotan 2, which is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis that is known as alpha-Melanocyte stimulating hormone. MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido.
 


PT-141 Application

PT-141 is a synthetic amino acid protein discovered during clinical trials using the Melanotan 2 for sunless tanning, photo-protection results from melanotans. The melanocortin system targets receptors associated with desire through the melanocyte stimulating hormone paths that cross the blood-brain-barrier. Potentially the powerful sex-drug results feeling an aphrodisiac experience amplifying arousal pt141 reviews have shown the ability to increase libido effects of both men and women
 
Potential benefits

For  Men:

effective in a broad range of patients, including those with severe ED and those non-responsive to sildenafil
efficacy in "at-home" studies is comparable to PDE-5 inhibitors
up to 50% of ED patients were restored to a normal level of function
co-administration with sildenafil shows superior efficacy
side effects include facial flushing, nausea, aftertaste and post-nasal drip

For  Women:

Palatin conducted a Phase 2A study in 18 premenopausal women with a diagnosis of female sexual
dysfunction (FSD). Patients reported a significant increase in sexual desire and in genital arousal after
receiving PT-141, compared to
placebo. Additionally, there was a correlation between sexual desire and genital arousal in patients receiving
PT-141, an observation that further reinforces the potential importance of these reports.

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