China successfully developed the world's first high-compensation depth living human retinal imaging system

Release date: 2008-06-30

China successfully developed the world's first high-compensation depth living human retinal imaging system
Our scientific and technological personnel have successfully developed the world's first high-compensation depth living human retinal imaging system - high-definition fundus imaging liquid crystal aberration compensator. Recently, the latest research results, which was completed by Xuan Li, a researcher at the Changchun Institute of Optics and Mechanics, Chinese Academy of Sciences, passed the expert appraisal organized by the Science and Technology Department of Jilin Province in Changchun.
The human retinal nerve tissue belongs to the ectoderm, and the blood vessel belongs to the middle blast, which is the only small blood vessel in the human body that can be directly seen. Clinically, the systemic lesions are often judged according to changes in the fundus, such as cardiovascular and cerebrovascular diseases, endocrine disorders, arteriosclerosis, hypertension, central serous choroidal retinopathy, and early diabetes. Therefore, fundus examination is not only an important basis for the diagnosis of ophthalmic diseases, but also an important means of examining the extent of other diseases in the body and understanding the prognosis.
According to experts, the smallest blood vessels in the human eye are about 5 microns in diameter. The existing fundus testing equipment can only be resolved to 20 micrometers. In order to overcome this problem, in 2005, the research team led by Xuan Li of the Changchun Institute of Optics and Mechanics of the Chinese Academy of Sciences undertook Jilin. The development task of the provincial high-tech fundus imaging liquid crystal aberration compensator, after nearly three years of hard work, has achieved a series of innovative results: the development of a 260,000 drive unit suitable for ophthalmic applications Liquid crystal wavefront corrector; using the phase diagram technology to achieve large distortion correction of 800 degree myopia and 200 degree astigmatism in the human eye, both can achieve high resolution imaging of visual cell contour of about 3 microns; Adapt to the bottleneck problem of low energy utilization of the system; adopt high-speed wavefront numerical analysis technology to make the imaging speed meet the video requirements.
Experts in the appraisal committee believe that this high-definition fundus imaging liquid crystal aberration compensator can achieve a high resolution of 3 microns, which can distinguish the vascular area on the most tiny blood vessels, not only can clearly reveal retinal cells, but also because of the system The liquid crystal corrector has a 260,000 drive unit, and has the same resolution compensation imaging effect for myopia of 800 degrees and below and astigmatism of 200 degrees or less. The research results are original and help to greatly improve the level of medical testing. At the same time, because this imaging test is completely harmless, the universality of the instrument can be used as a universal health check to facilitate the diagnosis of early diseases. More importantly, the new topic “Retina Transplantation and Neural Stem Cell Transplantation”, which saves the blind, has not yet found an effective means of observing nerve cell tissue. This device offers this possibility.
At present, the system has begun to enter clinical trials and is ready for industrialization. As this result has completely independent intellectual property rights, Jilin Province will give full support to it. ——Shanghai Medical Device Industry Association website

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