Chicken gout is characterized by dystrophy of protein metabolism or damage to the kidneys, leading to the accumulation of urate in the body's metabolism of metabolic disorders, the pathological features of the accumulation of large amounts of uric acid in the blood, causing weight loss, weakness, diarrhea, white row of thin Feces and other symptoms. The broiler chickens raised in a broiler farm in Hejian City, Hebei Province, suddenly developed this disease. The situation was as follows:

Incidence 2500 broiler chickens raised by Kwak farms were well-growth and were immunized according to normal immunization procedures. On the 20th day, chickens were found to have diarrhea and white feces. The appetite decreased and more than 20 died each day.

At the onset of the onset of clinical symptoms, appetite decreased, water intake increased, chicken cocks were pale, and the spirit was depressed. Feathers were unkempt, gradually emaciated, legs were weak, joints were swollen, and they were reluctant to exercise. Diarrhea was caused by white lime-like excrement and contaminated feathers around the anus. Some diseased chickens are highly dilated and a small amount of light yellow or colorless turbid liquid flows out of the mouth.

Pathological changes A total of more than 10 sick and dead chickens were co-dissected and 5 were found dead. The liver was swollen and blood stasis. Some pericardial effusions, pericardium, and airbags were covered with urate-like urate; kidneys were swollen and the color was changed. Lightens, the surface has a white rugged pattern, crisp, ureteral obstruction was significantly thickened by urate, filled with a large number of milky lime-like deposits, joint swelling in a large number of urate deposition; some heart, liver, The spleen, mesentery and peritoneum were covered with a layer of bue urate, severely forming a white film, and white urate deposits in the tracheal mucosa. Individual broilers have a large amount of light yellow liquid inside the abdominal cavity and are jelly-like.

Laboratory inspection

1. Aseptically, the heart, liver, spleen, and kidneys were smeared. After Gram stain, microscopic examination of the cells was not performed. The cells were inoculated on an ordinary agar medium and incubated in a 37°C incubator for 48 hours. Colonies grow.

2. The plump feathers of the diseased chickens and the standard serum of the infectious bursal were used for the agar diffusion test. The results were negative.

3. The white matter in the ureter was observed under a low magnification microscope and a large number of needle-like urate crystals were observed.
4. The crude protein content of the feed was 23.5%, crude fiber content was 5.0%, calcium was 0.8%, phosphorus was 0.7%, and salt was 0.6%. The results showed that the content of crude protein was high.

The diagnosis was based on the onset, clinical symptoms, pathological changes, and laboratory test results and diagnosed as broiler chicken gout.

treatment

1. First, reduce the amount of protein in the feed, and feed millet, corn, green feed, etc. 1 timely pick out the diseased chicken, given rhubarb soda 2 / only, oral rehydration salt drinking water; 2 discontinue sulfa drugs, the whole group with 0.2% kidney detoxification spirit and glucose drinking water, 2 times / day; 3 poplar Sodium and equivalent amounts of sodium bicarbonate were added at the same time with appropriate amounts of aminophylline, 2 times per day for 5 days, which promoted the excretion of urate in the body. 3 Add gentamicin to drinking water to prevent secondary infection, 2 times per day.

2. The Chinese herbal medicine with detoxification, blood circulation, and diuretic swelling in the feed: Radix isatidis, honeysuckle, 1000 g of plantain, 500 grams of dried tangerine peel, and 50 grams of Salvia miltiorrhiza, and 200 grams of licorice for fine grinding (1 g per chicken), boiled water Dip leaching medicine, let cool, medicine and dregs together in the feed, add poultry feed supplement, 2% cod liver oil. At the same time increase the lighting time, increase the appropriate sports.

After changing the feed, after the above treatment, the symptoms decreased after 5 days, the number of dead chickens gradually decreased, and the flock returned to normal.

summary

1. The occurrence of gout is generally related to long-term and large-scale feeding of feeds rich in high protein, vitamin deficiency, lack of exercise, insufficient drinking water, and infectious diseases.

2. Sulfa drugs are commonly used drugs, such as excessive or long-term administration will cause or aggravate renal function damage, so that accumulation of urate in the body, causing chicken gout death. The family had a large dose of prolonged use of multiple sulfa drugs, which was another important factor in aggravating gout death in chickens.

3. Poultry houses are humid and poorly ventilated, which also aggravates chicken gout.

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