Release date: 2007-11-05

Chinese scientists obtain retinal tomography images of human eyes for the first time Recently, the OCT-AO imaging technology and its application research in ophthalmology have been made by the Institute of Optoelectronics Research Institute of the Chinese Academy of Sciences. The project obtained a clear image of the human eye retinal tomography, marking a substantial progress in the key technology research of human retinal imaging in vivo.
At present, the fundus retina high-resolution imaging technology mainly includes adaptive optical fundus camera, adaptive optical confocal scanning ophthalmoscope and adaptive optics coherence tomography, and corrects human eye aberration through Adaptive Optics (AO) system. A lateral resolution close to the diffraction limit can be obtained. However, adaptive optical fundus cameras have very low longitudinal spatial resolution and generally only have images of the retinal surface and the visual cell layer. The ultimate longitudinal spatial resolution of adaptive optic confocal scanning ophthalmoscopes does not meet the high-resolution tomography of the retinal multilayer structure of the fundus.
Optical coherence tomography is an imaging technology developed rapidly in the past decade. It uses the basic principle of weak coherent optical interferometer to detect the back reflection or several scattered signals of different depth layers of biological tissue facing incident weak coherent light. By scanning, a two-dimensional or three-dimensional structure image of the biological tissue can be obtained. It has a high vertical spatial resolution, can reach 1 ~ 15μm, is 1-2 orders of magnitude higher than the ultrasonic detection technology, and has non-contact, which is called high-resolution tomography of the multi-layer fine structure of the fundus retina. The best means. If the OCT technology is combined with the AO technology, the AO system is used to correct the human eye aberration, and the fundus retina image with high lateral and vertical resolution is obtained, which lays a foundation for the reconstruction of the fundus three-dimensional high-resolution image, which will be related diseases. Early diagnosis, condition monitoring, drug efficacy evaluation, biometrics, and related medical research provide unprecedented tools.
The successful acquisition of living human retinal tomography images lays a solid technical foundation for the ultra-early diagnosis of ophthalmic diseases and systemic related diseases in China in the “non-invasive” state, thus laying a solid foundation for the formation of a new generation of high Resolving bio-optical imaging technology, improving the diagnosis and treatment of fundus diseases, and promoting the health of citizens is of great significance.

——China Medicine 123 Network

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