With the gradual popularization of molecular biology research, the demand for gel imaging systems in China is growing. Whatever the purpose, the components of gel imaging systems are similar. There is a shooting system, a black box with a special light source and software for acquiring and analyzing gel images. However, most gel imaging systems offer different product characteristics to meet the needs of different scientific research. Rapidly evolving electronic technology, optical technology and imaging analysis software make imaging operations more user-friendly.
Currently imported products are mainly Bio-Rad products, ChemiDoc XRS system is designed for high-resolution chemiluminescence and fluorescence imaging applications. Features of the system include a 1.3 mega super cooled CCD camera, a tightly opaque darkroom, a sliding transilluminator, a software-controlled zoom, focus, aperture, real-time imaging and dynamic flat field telescope. Another more basic model, the Gel Doc XR, is designed for fast, high-resolution imaging but without chemiluminescence imaging. The system consists of a darkroom, a 1.4 megapixel CCD camera, UV and white illumination, amber filter slides and a UV shield. The Gel Doc XR system can also be upgraded to the ChemiDoc XRS system, both of which include image acquisition and analysis software, Quantity One. Bio-Rad also offers two higher resolution and more sensitive gel imaging system models: VersaDoc Model 4000 and VersaDoc Model 5000. The VersaDoc Model 4000 system features a 3.2 megapixel CCD camera that provides the best resolution. The system is especially useful for proteomic analysis. For example, Quantity One 1-D analysis software can be used to estimate the molecular weight and quantity of protein samples. PDQuest 2-D analysis software can also be used to analyze differences in protein expression products.
The well-known Alpha Innotech also offers a wide range of products for scientific research and budgetary requirements, such as the current relatively new and high-end products - FluorChem SP, which can be used for chemiluminescence, fluorescence, and Products for visible light applications. High resolution (scientific level CCD), 4 megapixels, low signal to noise ratio, dark current, absolute and adjustable cooling temperature (for higher end systems). Alpha Innotech's AlphaEaseFC software, its unique algorithm improves imaging resolution through 3D image contour imaging, image sharpening and reduced signal-to-noise ratio. AlphaEaseFC software provides easy-to-use click-through 1D lane analysis, 2D dot density, MW/Rf (molecular weight/mobility) calculations, cloning and cell counting, microtiter plate analysis, microarray analysis, object distance measurement and gelation Ratings and other features.
Alpha Innotech also offers users an affordable AlphaDigiDocRT 2 product, a real-time gel imaging system that can be used with a single computer (via USB connection) and a UV transilluminator.
In addition, Kodak's molecular imaging system is described by its senior marketing specialist Allison Sova: "Kodak's Gel Logic gel imaging system family allows researchers to choose the performance they need today and can be economical in the future. A simple upgrade system to meet future needs. Simply put, Kodak offers researchers greater flexibility to meet their lab's ever-increasing imaging capabilities, and is an upgradeable system.
Kodak's Gel Logic 100 is Kodak's basic imaging system, which includes a 1 megapixel digital CCD camera, a Gel Logic imaging operating room, and an ethidium bromide bandpass filter. And Kodak's award-winning Molecular Imaging software provides features not found in other imaging systems that can be used on Mac or Windows operating systems.
The Gel Logic 2200 Digital Imaging System is Kodak's top gel imaging system. The Gel Logic 2200 utilizes a 2.2 megapixel cooled CCD camera for higher sensitivity chemiluminescence and low brightness fluorescence detection. The system also incorporates white and ultraviolet light sources. According to Kodak, the system is capable of detecting fluorescent signals from picomolar to femtomol levels, achieving the same sensitivity as radioactive self-developing films.
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